Oxidation Velocity of Modified Oxyhemoglobin by Sodium Nitrite
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چکیده
منابع مشابه
OXIDATION OF OXYHEMOGLOBIN BY SODIUM NITRITE A kinetical study on the oxidation of hemoglobin to methemoglobin by nitrite
The detailed mechanism of the reaction was further clarified by Martin et al4) in 1963 by investigating the relationship between the molecular structure of hemoglobin and the rate of the oxidation by nitrite. In these studies, however, the significance of the initial phase of the reaction, which will be clarified in the present paper, was insufficiently understood. As shown in Fig. 1, two phase...
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Oxidation of oxyhemoglobin by nitrite is characterized by the presence of a lag phase followed by the autocatalysis. In phosphate buffer, an asymmetric ESR signal is detected at g = 2.005 (hereafter referred to as the g = 2 radical) during the oxidation which is similar to that of the methemoglobin free radical generated from methemoglobin and H2O2. Catalase and KCN prolong the oxidation, indic...
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A novel chemically modified electrode containing Prussian blue complex was achieved on the surface of glass carbon electrode by sol-gel technique. The electrochemical behavior of modified electrode was characterized by cyclic voltammetry in detail. The film electrode obtained was very stable and exhibited electrocatalytic response for oxidation of nitrite. Results showed at bare GC electrode, a...
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The effect of sodium nitrite, amyl nitrite and nitroglycerin (glyceryl trinitrate) on the hemoglobin of adult erythrocytes was examined in vitro. Both amyl nitrite and nitroglycerin reacted immediately with oxyhemoglobin to effect oxidation into methemoglobin while sodium nitrite required an inductionary period (lag phase) prior to the reaction. Kinetic studies of the biomolecular rate law for ...
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Preliminary data on the kinetics of the oxidation of nitrite by Nitrobacter were presented by Laudelout & van Tichelen (1960). The present observations complete and extend the results concerning the effects of pH, concentrations of nitrite and of nitrate, temperature and oxygen partial pressure on the parameters of the rate equation for the oxidation of nitrite by intact cells and cell-free ext...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1965
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.7.4_258_1